Example

A valid input file must be in one of the two following options (csv format):

  1. 12 columns with these headers:
    FAMCODE, BIRTHSEQ, A1, A2, B1, B2, C1, C2, DRB11, DRB12, DQB11, DQB12

    • FAMCODE: family index (starting from 1)
    • BIRTHSEQ: for father- F, for mother- M, for children – child index (starting from 1)
    • A1, A2, B1, … : HLA typing for each allele.
      For example: high resolution: 02:01 ; low resolution: 02 ; low resolution with letter codes: 02:AG ;
      or leave empty (if you do not have data for allele)

    A simple example:

    FAMCODE BIRTHSEQ A1 A2 B1 B2 C1 C2 DRB11 DRB12 DQB11 DQB12
    1 F 02:01 30:04 40:01 51:22 03 14 04:01 14:02 03:02 03:02
    1 1 24:02 02:01 14:02 06:02 13:01 04:01
    1 2 02:01 02:01 40:01 57:01 04:01 07:01
    2 M 03 02 07:02 13:02 15:01 01:01 06:02 05:01
    2 1 02:01 01:CNJK 04 06 02:01 06:02

  2. 3 columns with these headers:
    FAMCODE, BIRTHSEQ, GLSTRING

    • FAMCODE and BIRTHSEQ: as mentioned in section 1.
    • GLSTRING: HLA typing in gl string format:
      A*___+A*___^B*___+B*___^C*___+C*___^DRB1*___+DRB1*___^DQB1*___+DQB1*___
      For example: A*02:01+A*30:04^B*03:04+B*14:02^B*40:01+B*51:22^DRB1*04:01+DRB1*14:02^DQB1*03:02+DQB1*03:02
      The gl string can be with missing data: A*02:01+A*30:04^B*40:01+B*51:22^DRB1*04:01+DRB1*14:02

    A simple example:

    FAMCODE BIRTHSEQ GLSTRING
    1 F A*02:01+A*30:04^B*40:01+B*51:22^C*03+C*14^DRB1*04:01+DRB1*14:02^DQB1*03:02+DQB1*03:02
    1 1 A*24:02+A*02:01^C*14:02+C*06:02^DRB1*13:01+DRB1*04:01
    1 2 A*02:01+A*02:01^B*40:01+B*57:01^DRB1*04:01+DRB1*07:01
    2 M A*03+A*02^B*07:02+B*13:02^DRB1*15:01+DRB1*01:01^DQB1*06:02+DQB1*05:01
    2 1 A*02:01+A*01:CNJK^C*04+C*06^DQB1*02:01+DQB1*06:02

  3. PED format (not recommend to users).
    10 columns with the headers: Family_ID, Individual_ID, Paternal_ID, Maternal_ID, Sex, Phenotype, Hap1, Race1, Hap2, Race


Each of the files above could contain an additional column: 'RACE'.
In this column, you can fill the known races about the family you insert.
Format: uppercase, separated by '+'. Note: you have to fill the same races for each member of the family.
You can fill races for some of the families and leave empty for the others (see "Download example of a valid file - option 2, with races)
List of all the races is available in "Races" section.
An example which contains races:

FAMCODE BIRTHSEQ A1 A2 B1 B2 C1 C2 DRB11 DRB12 DQB11 DQB12 RACE
1 F 02:01 30:04 40:01 51:22 03 14 04:01 14:02 03:02 03:02 AAFA+AINDI+CAU
1 1 24:02 02:01 14:02 06:02 13:01 04:01 AAFA+AINDI+CAU